Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture (DC-US)

Mohamed Maher Ismail Ahmed Elashmawy

Status: Enrolling

Conditions: Dupuytren Contracture

Treatments: Procedure: Ultrasound guided needle knife dissection

Study type: Interventional

Funder types: Other

Identifiers

NCT06788847

R.24.12.2966 (Registry Identifier)

MansouraUH_DC-US_2025

Details and patient eligibility

About

This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.

Full description

Dupuytren's contracture is a disease mainly characterized by the progressive fibrosis of the palmar fascia with subsequent hand deformity and dysfunction. The current study seeks to explore, through this minimally invasive technique, ultrasound-guided needle knife dissection regarding ROM and patient satisfaction. The procedure will be carried out under ultrasound guidance to ensure safety and completeness with the accuracy of precise dissection. Primary outcome measures will concern hand mobility, and secondary measures will evaluate patient self-reported satisfaction and any complications for the 6-month follow-up period.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants diagnosed with Dupuytren's Contracture.
• Willing to undergo ultrasound-guided needle knife dissection

Exclusion criteria

• Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.
• Active hand infections, open wounds, or dermatological conditions in the treatment area.
• Coagulopathy or use of anticoagulant that cannot be safely paused
• Neuromuscular disorders affecting hand function
• Pregnancy or breastfeeding
• Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease.
• Known hypersensitivity to local anesthetics.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Intervention Group: Ultrasound-Guided Needle Knife Dissection

Experimental group

Description:

Participants in this group will undergo ultrasound-guided needle knife dissection for the treatment of Dupuytren's Contracture. Local anesthesia using 3-5ml of 1% lidocaine 0.25% bupivacaine is administered for patient comfort. This procedure is designed to improve hand function with minimal complications.

Treatment:

Procedure: Ultrasound guided needle knife dissection