Evaluation and Management for Prostate Oncology, Wellness, and Risk (EMPOWeR)

Sidney Kimmel Cancer Center at Thomas Jefferson University

Status: Completed

Conditions: Prostate Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT03807492

18D.644

JT 13180 (Other Identifier)

Details and patient eligibility

About

The EMPOWeR study is proposed as a cohort study with longitudinal follow-up to determine rates of genetic mutations among men with or at-risk for prostate cancer to address the various facets of genetic education and counseling for optimized genetic assessment and wellness of men. The results will inform practice guidelines and future studies for maximal impact of genetic evaluation of men for inherited prostate cancer.

Enrollment: 241 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men with a personal history of prostate cancer
• Unaffected males who are at higher risk for prostate cancer (family history of prostate cancer or African American males)
• Men who previously tested positive for a mutation may be eligible for Specific Aims 2-7
• Men with a known familial mutation
• Men who previously participated in the Genetic Evaluation of Men (GEM) study (IRB#14S.546) will be offered participation in EMPOWeR -

Exclusion criteria

• Age < 18 years
• Mental or cognitive impairment that interferes with ability to provide informed consent

Trial design

241 participants in 1 patient group

EMPOWeR Study

Description:

This is a cohort study, with initial patient assessments and longitudinal follow-up. Participation of subjects will be indefinite, which will be discussed in the informed consent.