Evaluation of a Cognitive Remediation Program for Mood Disorders (ECO-DBP)

Centre hospitalier de Ville-Evrard, France

Status: Unknown

Conditions: Taking Charge of Cognitive Impairment in Patients With Mood Disorders

Treatments: Behavioral: Evaluation

Study type: Interventional

Funder types: Other

Identifiers

NCT04354974

10477M-ECO-DBP-2019

Details and patient eligibility

About

Psychotherapeutic management of cognitive disorders in patients suffering from a mood disorder

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age between 18 and 65 years old
2. The patient's previous diagnosis of Bipolar-Related Disorder or Depressive Disorder according to the DSM-5 criteria.
3. Mood stabilized with respect to depressive symptomatology (absence or presence of residual mild depressive symptoms (HDRS-17 ≤ 18))
4. Mood stabilized with respect to manic symptomatology (absence or presence of residual mild manic symptoms (YMRS ≤ 8))
5. Stable and effective treatment at minimum dose for at least 2 months
6. Cognitive complaint expressed by the patient, and detected by the patient's referring psychiatrist
7. Free and Informed Consent Form read, initialled and signed
8. Patient affiliated to a social protection scheme or beneficiary of State Medical Aid
9. Patient knowing how to speak French -

Exclusion criteria

1. Presence of a DSM-5 disorder, other than a mood, anxiety or personality disorder
2. Substance addiction or abuse (Alcohol, psychoactive substances) in the past 12 months
3. Manic, hypomanic or major depressive episode in the last 2 months
4. Somatic or neurological disorder which may lead to cognitive impairment
5. Current or less than one month's commitment to another research protocol
6. A neuropsychological assessment prior to 6 months.
7. Patient under protective custody, guardianship or reinforced guardianship

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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36 participants in 2 patient groups

Eco Program (Ecological Cognitive Training for Mood Disorders)

Active Comparator group

Description:

Duration: four months, 16 sessions * Frequency: One one-hour session and one hour of personal work per week * Modalities: Paper and pencil exercises and manipulable tools * Objective: Learning problem-solving strategies for use in daily life * Modules: Psychoeducation, Information Processing, Memory, Concept Formation, Functional Disorders

Treatment:

Behavioral: Evaluation

ThOR Program (Remission Oriented Therapy)

Active Comparator group

Description:

Duration: four months, 16 sessions * Frequency: One one-hour session and one hour of personal work per week * Modalities: Paper tools and verbal exchange with the patient * Objective: Improvement of the patient's quality of life * Themes: Mood, social skills, autonomy, motivation, sleep

Treatment:

Behavioral: Evaluation