Evaluation of a Low-fluoride Anticaries Toothpaste

Indiana Nanotech

Status: Completed

Conditions: Tooth Abnormality

Treatments: Drug: Fluorides, Topical

Study type: Observational

Funder types: Other

Identifiers

NCT01094210

1R43DE020998-01

Details and patient eligibility

About

The purpose of this trial is to evaluate the anticaries remineralizing potential of a toothpaste containing 500 ppm fluoride plus fTCP technology relative to a commercially available toothpaste via a double-blind cross-over in situ (or intra-oral) clinical model, whereby approved human participants will wear an orthodontic appliance fitted with an enamel specimen for the duration of a leg (28 days). There will be two test legs.

Enrollment: 30 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 30 adult subjects (between 18-50 years of age)

Trial design

30 participants in 2 patient groups

G1

Description:

500 ppm F Test Toothpaste

Treatment:

Drug: Fluorides, Topical

G2

Description:

1100 ppm F Control Toothpaste

Treatment:

Drug: Fluorides, Topical