Evaluation of a Multidisciplinary Care Pathway on the Evolution of Renal Function in Patients With Advanced Chronic Kidney Disease

Centre Hospitalier Universitaire de Saint Etienne

Status: Active, not recruiting

Conditions: Chronic Kidney Disease stage4; Chronic Kidney Disease Stage 5

Treatments: Diagnostic Test: Evolution of renal function; Diagnostic Test: Measure sodium and protein consumption; Diagnostic Test: Measurement of biological parameters; Behavioral: Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L); Diagnostic Test: Measurement of haemoglobin levels

Study type: Observational

Funder types: Other

Identifiers

NCT06495385

IRBN1502023/CHUSTE

Details and patient eligibility

About

The number of incident and prevalent patients with end stage renal disease on dialysis treatment is increasing in France and worldwide. A quarter of dialysis patients are initiating dialysis urgently through central venous catheters and the number of patients registered in the waiting list for renal transplantation before dialysis initiation is very low. This is also reflected in the very low number of pre-emptive renal transplantations.

In order to reduce the number of dialysis patients, the French state has induced a national program proposing a multidisciplinary care pathway including the nephrology visits and at least one consultation with a dietitian and a specialist renal nurse in all patients with Chronic Kidney Disease stage 4 and 5.

Full description

The aim of this single-center retrospective study is to evaluate the influence of the complete, partial or no participation in this program on the evolution of renal function and clinicobiological parameters in this group of patients.

Enrollment: 535 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All stage 4 and 5 Chronic Kidney Disease patients that were included in the program from 01/01/2021 to 31/12/2021 in the clinics of AURA SANTE

Exclusion criteria

• Patients without a medical follow up during this year (2021)
• Patients with insufficient or no data during the 24 month of follow up period
• Active treatment with corticosteroids, cytotoxic or immunosuppressive drugs, ongoing infection, autoimmune disease or active tumor process.

Trial design

535 participants in 3 patient groups

Study group

Description:

Full participation (medical + dietitian+ specialist nurse)

Treatment:

Diagnostic Test: Measurement of haemoglobin levels

Behavioral: Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L)

Diagnostic Test: Measurement of biological parameters

Diagnostic Test: Measure sodium and protein consumption

Diagnostic Test: Evolution of renal function

Control 1

Description:

Partial participation (medical+ dietitian OR specialist nurse)

Treatment:

Diagnostic Test: Measurement of haemoglobin levels

Behavioral: Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L)

Diagnostic Test: Measurement of biological parameters

Diagnostic Test: Measure sodium and protein consumption

Diagnostic Test: Evolution of renal function

Control 2

Description:

No participation (medical visit only)

Treatment:

Diagnostic Test: Measurement of haemoglobin levels

Behavioral: Quality of life questionnaire EUROQOL 5 dimensions (EQ-5D-5L)

Diagnostic Test: Measurement of biological parameters

Diagnostic Test: Measure sodium and protein consumption

Diagnostic Test: Evolution of renal function