Evaluation of a Multilevel Intervention on Adult COVID-19 and Influenza Vaccination Rate

Mayo Clinic

Status: Enrolling

Conditions: COVID-19 Immunisation; Influenza Vaccine

Treatments: Behavioral: Patient letter and clinician communication

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT06646406

24-007738

Details and patient eligibility

About

The study will test two tactics to improve uptake of two vaccines in adults. The vaccines prevent COVID-19 and influenza. Both are common and harmful. Most adults do not get either vaccine. This is despite strong recommendations that all adults get both vaccines.

The study will involve adult patients at eight Mayo Clinic primary care practices in Rochester and Kasson. The study will test the two tactics together. Four clinics will get the two tactics. The other four clinics will not. The study will randomly assign the two tactics to the clinics. One tactic is to send a letter by US mail to the patient. The letter will state strong recommendations on getting both vaccines now. It will tell patients how to get the vaccines now. The second tactic is to send monthly emails to clinicians. It will remind them to use every visit to vaccinate patients against COVID-19 and influenza. The study will compare the uptake of the two vaccines after six months in the clinics with and without the two tactics.

Enrollment: 117,780 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients 19 years and older
• Patients empaneled to 1 of 8 adult primary care practices as of September 2024

Exclusion criteria

• Patients 18 years or younger
• Patients not empaneled to 1 of 8 adult primary care practices as of September 2024

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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117,780 participants in 2 patient groups

Patient letter and clinician communication

Experimental group

Description:

Each patient will be mailed a letter and each patient's clinician will receive a monthly email communicating information about making a strong recommendation for influenza and COVID-19 vaccination

Treatment:

Behavioral: Patient letter and clinician communication

No intervention

No Intervention group

Description:

No intervention