Evaluation of a Non-invasive Device to Measure Blood Pressure and Difference in Pulse Pressure (dPP) Intraoperatively

Johannes Gutenberg University (JGU)

Status: Completed

Conditions: Blood Pressure

Study type: Observational

Funder types: Other

Identifiers

NCT02009020

837.531.11 (8073)

Details and patient eligibility

About

Dynamic parameters like pulse pressure Variation (PPV) , synonymous: difference in pulse pressure (dPP), can predict fluid responsiveness reliably (Marik PE et al, Crit Care Med 2009; 37:2642-7). An arterial line is required for assessment of dPP. On a modified Penaz technique, a non-invasive measurement device is now available commercially. In this study, the reference technique based on arterial measurement and a respiratory variation monitor (Pestel G et al, Anesth Analg 2009; 108:1823-9) was compared to the non-invasive device a clinical setting. At defined time points, systolic, diastolic, mean arterial blood pressure and dPP were compared using Bland-Altmann Analysis (Bland JM, Altman DG, Lancet 1986; 1: 307-10)

Enrollment: 26 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 and < 80 years old
• Written informed consent obtained
• Patients scheduled for elective urological or abdominal surgery procedures in supine position
• qualifying for arterial line

Exclusion criteria

• pregnancy
• cardiac insufficiency (NYHA 4, EF < 25 %)
• coronary artery disease (CCS 4)
• coagulopathy
• symptoms of infection or sepsis
• malignant hyperthermia
• absence of sinus rhythm
• BMI > 30
• M. Raynaud

Sponsor of this trial

Lead Sponsor

Johannes Gutenberg University (JGU)