Evaluation of a Question Prompt List for Patients With Myelodysplastic Syndromes (QPL-MDS)

Institut Paoli-Calmettes

Status: Unknown

Conditions: Myelodysplastic Syndromes

Treatments: Behavioral: Question prompt list (QPL); Behavioral: Education brochure of Groupe Français des Myélodysplasies

Study type: Interventional

Funder types: Other

Identifiers

NCT02781441

QPL-MDS-IPC 2014-013

Details and patient eligibility

About

MDS are a diverse group of hematopoietic malignancies, which mainly occur in patients over 75 years of age. Incidence rate in 2012 in France was more than 6 cases per 100 000 person-years. MDS are characterized by ineffective haematopoiesis causing cytopenia, and by leukemic transformation. The disease is heterogeneous, its pathophysiology complex and clinical evolution variable.The few data available on MDS patients show how difficult it is to understand MDS, its prognosis and the reasons for prescribing or not some treatments. In the context of a highly complex potentially lethal disease such as MDS, it is of utmost importance to optimize the information conveyed to patients. Particularly, 70.5% of MDS patients surveyed in our developmental study would have preferred more information about prognosis at diagnosis disclosure.

A simple intervention based on the use of a question prompt list (QPL), would greatly improve the information process by helping patients to express their main concerns at their medical consultations. Cultural differences may exist in the appraisal of QPLs and QPLs have not yet been widely used in France.

However, in line with the previous results available in the literature and in a context a priori favourable to the use of such an instrument, the investigators hypothesise that use of a QPL will increase MDS patients' expressions of concerns and questions at their medical consultations. Particularly the investigators assume that the discussion about prognosis will be facilitated, without increasing anxiety because patients remain free to ask or not for such information. The use of QPLs would also be a way to limit social inequalities related to insufficient information and to encourage patient-doctor communication and meeting of patient preferences which could lead to better health outcomes.

Enrollment: 140 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients newly referred for a MDS in one of the participating centres
• Older than 18
• Able to answer a self-administered questionnaire
• Having signed an informed consent
• affiliated to the French Social Security System

Exclusion criteria

• emergency,patients deprived of liberty or placed under the authority of a tutor

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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140 participants in 3 patient groups

Control group

Active Comparator group

Description:

Patients will receive only the education brochure of GFM

Treatment:

Behavioral: Education brochure of Groupe Français des Myélodysplasies

General QPL group

Experimental group

Description:

Patients will receive the brochure and the newly developed QPL (general version)

Treatment:

Behavioral: Education brochure of Groupe Français des Myélodysplasies

Behavioral: Question prompt list (QPL)

Targeted QPL group

Experimental group

Description:

Patients will receive the brochure and the newly developed QPL (general version)

Treatment:

Behavioral: Education brochure of Groupe Français des Myélodysplasies

Behavioral: Question prompt list (QPL)