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Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome (SAOS/T21)

C

Centre Hospitalier Universitaire de Saint Etienne

Status

Completed

Conditions

Down Syndrome

Treatments

Other: Polysomnography

Study type

Observational

Funder types

Other

Identifiers

NCT00951730
0808017
2008-A01273-52 (Other Identifier)

Details and patient eligibility

About

People with Down syndrome are at increased risk of sleep apnea, not only from obstruction of the upper airway, but also of central origin. According to published data, sleep apnea may occur in at least 40% of children and adults with Down syndrome. Consequences of these sleep apnea are numerous : failure to thrive, cognitive decline, high blood pressure, heart disease, accident due to day sleepiness, fatigue. This condition is treatable in people with Down syndrome, as it is in ordinary people.

Diagnosis of sleep apnea in people with Down syndrome is therefore a major concern. In addition, data regarding age of apparition of this complication are missing, making repeated screening necessary.

Polysomnography is the method of choice for the diagnosis of sleep apnea. Unfortunately, it is time consuming and sleep departments are heavily busy.

Full description

The main objective of our study is to evaluate an easier screening strategy combining questionnaire and overnight recording of few data, compared to polysomnography.

We hope our strategy will permit regular screening for people with Down syndrome, helping us to draw guidelines for the survey of sleep apnea in this population.

Enrollment

97 patients

Sex

All

Ages

2+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Down syndrome
  • Patient (or parents of children) affiliated in a Social Regimen
  • Written consent signed (by parents for the children)

Exclusion criteria

  • Severe heart failure
  • Insufficient autonomy
  • Diagnosis of insanity, or behavioural problems

Trial design

97 participants in 1 patient group

Down syndrome
Description:
Adult and children with Down syndrome.
Treatment:
Other: Polysomnography

Trial contacts and locations

3

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Data sourced from clinicaltrials.gov

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