Evaluation of Advanced US Tools in Assessing Allograft Complications

Imperial College London

Status: Completed

Conditions: Chronic Kidney Diseases; Failure,Kidney; Renal Failure; Renal Artery Stenosis; Complications; Fibrosis

Treatments: Device: 3D imaging

Study type: Observational

Funder types: Other

Identifiers

NCT04423458

848 -20HH6053

Details and patient eligibility

About

This study evaluates the role of advanced US technology in assessing renal transplants as screening tools such as 3D Ultrasound, Ultrasound SWE, and MFI besides current ultrasound conventional metheds.

Full description

This study will focus on monitoring renal after transplantation using all US advanced technology.

Aim one will concentrate on the 3D US in assessing artery stenosis (TRAS) compared to the gold standard.

Aim two focuses on will concentrate on Ultrasound elastography in assessing renal stiffness.

Aim three will compare US colour modes such as PD, CD and MFI to assess renal perfusion in three groups.

Duration: 18 Months; participants will have a patient information sheet; once they are happy to participate, consent will be obtained.

Study data will be entered into a database encrypted and stored in the department. Only the study principal investigator (PI) will know the study database password.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

INCLUSION CRITERIA

• Patients ≥ 18 years.
• Tx patients.
• Gender.

EXCLUSION CRITERIA

• Prisoners.
• Patients < 18 years.
• Pregnant women

Trial design

80 participants in 1 patient group

Transplanted kidney

Description:

No intervention is required. Routine Doppler assessment + 3D scan + Shear wave elastography + MicrFlow Imaging will be immediately recorded afterwards

Treatment:

Device: 3D imaging