Evaluation of Alteration by Magnetic Resonance Imaging (MRI) in Dementia Among Elderly Subjects (AMIMAGE)

University Hospital of Bordeaux

Status: Completed

Conditions: Alzheimer Disease; Dementia

Treatments: Other: Neuroimaging

Study type: Observational

Funder types: Other

Identifiers

NCT00951197

CHUBX2008/13

Details and patient eligibility

About

Capturing the earliest stages of Dementia especially Alzheimer's Disease (AD) is a great challenge. Until now the NINCDS-ADRDA and the DSM criteria for AD were largely used as diagnostic standards in research. However, the research on AD progresses and some biomarkers have been recently suggested to improve the diagnostic criteria of AD, such as cerebrospinal fluid markers, neuroimaging with Positon Emission Tomography (PET) or Magnetic Resonance Imaging (MRI).

Enrollment: 318 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• participate in the AMI cohort
• be aged 65 and older
• be retired from agricultural profession
• live in rural area in Gironde

Exclusion criteria

• contraindication of MRI
• left-handed
• severe dementia
• Parkinson's disease
• poor health incompatible with the transport to neuroimaging service
• to be left handed

Trial design

318 participants in 1 patient group

elderly subjects retired from agriculture

Treatment:

Other: Neuroimaging