Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft in Periodontal Intrabony Defects

Cairo University (CU) logo

Cairo University (CU)

Status

Completed

Conditions

Chronic Periodontitis

Treatments

Biological: Demineralized bone matrix in putty form
Biological: Amnion chorion membrane

Study type

Interventional

Funder types

Other

Identifiers

NCT02679209
Aminonchorion_DBM

Details and patient eligibility

About

A clinical and radiographic evaluation of 2 regenerative techniques, bioresorbable membrane and bone allograft for management of periodontal intrabony defects.

Full description

Twenty-two patients suffering from advanced chronic periodontitis were included in this randomized controlled clinical trial. Each subject contributed had two- or three-walled intrabony defects. Patients were randomly assigned into two groups; bioresorbable membrane or bone allograft. Clinical parameters were recorded at baseline and at 3 and 6 months postoperatively. Radiographic parameters were recorded at baseline and at 6 months postoperatively.

Enrollment

22 patients

Sex

All

Ages

35 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Severe chronic periodontitis patients.
  • having at least one site with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss as detected in periapical radiographs.

Exclusion criteria

  • Pregnant women
  • Having any given systemic disease
  • Taking any type of medication and/or antibiotic therapy during the 3 months before the study
  • Received periodontal treatment within the past 12 months Current or former smokers

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

22 participants in 2 patient groups

Bone allograft
Experimental group
Description:
commercially available demineralized bone matrix putty allograft will be used to fill in the defect after opening a periodontal flap
Treatment:
Biological: Demineralized bone matrix in putty form
Amnion chorion membrane
Experimental group
Description:
Amnion chorion commercially available allograft bioresorbable membrane as a guided tissue regeneration technique will be used to in the defect after opening a periodontal flap
Treatment:
Biological: Amnion chorion membrane

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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