Evaluation of Amnion Chorion Membrane and Demineralized Bone Matrix Putty Allograft in Periodontal Intrabony Defects

Cairo University (CU)

Status: Completed

Conditions: Chronic Periodontitis

Treatments: Biological: Demineralized bone matrix in putty form; Biological: Amnion chorion membrane

Study type: Interventional

Funder types: Other

Identifiers

NCT02679209

Aminonchorion_DBM

Details and patient eligibility

About

A clinical and radiographic evaluation of 2 regenerative techniques, bioresorbable membrane and bone allograft for management of periodontal intrabony defects.

Full description

Twenty-two patients suffering from advanced chronic periodontitis were included in this randomized controlled clinical trial. Each subject contributed had two- or three-walled intrabony defects. Patients were randomly assigned into two groups; bioresorbable membrane or bone allograft. Clinical parameters were recorded at baseline and at 3 and 6 months postoperatively. Radiographic parameters were recorded at baseline and at 6 months postoperatively.

Enrollment: 22 patients

Sex: All

Ages: 35 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Severe chronic periodontitis patients.
• having at least one site with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss as detected in periapical radiographs.

Exclusion criteria

• Pregnant women
• Having any given systemic disease
• Taking any type of medication and/or antibiotic therapy during the 3 months before the study
• Received periodontal treatment within the past 12 months Current or former smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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22 participants in 2 patient groups

Bone allograft

Experimental group

Description:

commercially available demineralized bone matrix putty allograft will be used to fill in the defect after opening a periodontal flap

Treatment:

Biological: Demineralized bone matrix in putty form

Amnion chorion membrane

Experimental group

Description:

Amnion chorion commercially available allograft bioresorbable membrane as a guided tissue regeneration technique will be used to in the defect after opening a periodontal flap

Treatment:

Biological: Amnion chorion membrane