Evaluation of an Apple Juice Drink With POs-Ca

Hitomi Mita

Status and phase: Completed; Early Phase 1

Conditions: Food Preferences

Treatments: Dietary Supplement: apple juice with 1.5% POs-Ca; Dietary Supplement: apple juice with 2% POs-Ca; Dietary Supplement: apple juice with 1% POs-Ca; Dietary Supplement: apple juice with 0.5% POs-Ca; Dietary Supplement: apple juice

Study type: Interventional

Funder types: Other

Identifiers

NCT01552252

POs-Ca02

Details and patient eligibility

About

The null hypothesis tested was that there are no differences in the taste palatability of the apple juices before and after adding POs-Ca.

Enrollment: 30 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adult subjects
• No eating or drinking within 30 minutes before the start time of the trials
• No tooth brushing within 30 minutes before the start time of the trials

Exclusion criteria

• apple hypersensibility

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

30 participants in 5 patient groups, including a placebo group

0% POs-Ca

Placebo Comparator group

Treatment:

Dietary Supplement: apple juice

0.5% POs-Ca

Active Comparator group

Treatment:

Dietary Supplement: apple juice with 0.5% POs-Ca

1% POs-Ca

Active Comparator group

Treatment:

Dietary Supplement: apple juice with 1% POs-Ca

1.5% POs-Ca

Active Comparator group

Treatment:

Dietary Supplement: apple juice with 1.5% POs-Ca

2% POs-Ca

Active Comparator group

Treatment:

Dietary Supplement: apple juice with 2% POs-Ca