Evaluation of an Arterial Calcification Score as a Predictive Factor of Anastomotic Leakage in Right Colectomy (RIGHTCOLOCALCI)

Centre Hospitalier Departemental Vendee

Status: Completed

Conditions: Right Colectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04002921

CHD 086-19

Details and patient eligibility

About

Anastomotic leakage is the major postoperative complication in right colectomy. Evaluation of calcification on coeliac trunk and mesenteric arteries on the preoperative CT scan could allow the identification of patient at-risk of postoperative complications.

A monocentric retrospective study performed at CHD Vendée concluded than a calcification score over or equal to 3 was associated with a higher risk of developping an anastomotic leakage.

The aim of this prospective multicentric study is to validate a calcification score based on preoperative CT scan analysis and focussing at coeliac trunk and mesenteric arteries.This study will involve patients operated on with a scheduled right colectomy.

Enrollment: 615 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years old
• Scheduled right colectomy with restoration of digestive continuity
• Patient who has had or will have a preoperative abdominal-pelvic CT scan with or without contrast injection
• Patient with the ability to understand the protocol and agree to participate in the study.
• Affiliated with a social security system

Exclusion criteria

• Patient requiring a right colectomy or ileocaecal resection for chronic inflammatory bowel disease or on long-term corticosteroid therapy
• Patient with a history of colic resection
• Patient under guardianship, curatorship, or deprived of liberty
• Pregnant, postpartum or breastfeeding women
• Minor patients

Trial design

615 participants in 1 patient group

Right colectomy

Description:

Patient with scheduled right colectomy and with a documented preoperative scan.