Evaluation of Anatomic and Visual Outcomes of Initially Closed Macular Holes

Sun Yat-sen University

Status

Completed

Conditions

Macular Holes

Study type

Observational

Funder types

Other

Identifiers

NCT01229657

2007B031302007 (Other Grant/Funding Number)

SunYat-senU

2008B030301306 (Other Grant/Funding Number)

Details and patient eligibility

About

To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with one to seven years of follow-up.

Full description

In recent years, peeling of the internal limiting membrane (ILM) has been used as a supplementary treatment to reducing the tangential tractional forces and inducing hole closure in macular hole surgery, and thus the anatomic success rate has increased to over 90%. However, despite these high rates of surgical success, the reopening of initially closed macular holes has also been observed from the first month to several years following surgery. Because about 45% to 95% of phakic patients frequently develop a progressive nuclear sclerosis cataract after macular hole surgery and require combined or subsequent cataract extraction to improve visual acuity, cataract extraction has become a potential factor in causing macular hole reopening, although this is still under debate. The purpose of this study is to describe the long-term anatomic and visual outcomes in patients who had initial anatomic success with macular hole surgery and who had postoperative follow-up of one or more years. All patient's charts were reviewed for age, macular hole stage (using the Gass classification), macular hole duration, epiretinal membrane of macula presence, ILM peeling, preoperative and postoperative visual acuity, rate of macular hole reopening, cataract extraction, and length of follow-up after vitrectomy.

Enrollment

79 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria