Evaluation of Antimicrobial Efficacy of Green Tea, Garlic With Lime, Pomegranate Extract and Chlorhexidine Mouth Rinses in a Group of Egyptian Children (In-Vivo Study)

omnia sayed

Status: Completed

Conditions: Dental Caries

Treatments: Procedure: Pomegranate extract mouth rinse; Procedure: Garlic with lime extract mouth rinse; Procedure: Green tea extract mouth rinse; Procedure: Chlorhexidine mouth rinse

Study type: Interventional

Funder types: Other

Identifiers

NCT05841589

PED18-8M

Details and patient eligibility

About

the aim of the clinical trial is to evaluate the antimicrobial efficacy of the herbal mouth rinses against chlorhexidine mouth rinse.

Full description

The present study was carried out on 84 children. Children were recruited based on certain inclusion criteria after signing a written informed consent by their parents. They were divided into 4 groups. Group (I) the children rinsed with Chlorhexidine mouth rinse, the child rinsed for 1 minute and plaque samples were collected from the child before and after rinsing. Group (II) children rinsed with green tea extract, while group (III) children rinsed with garlic with lime extract and group (IV) the children rinsed with pomegranate extract mouth rinse with the same procedures. .child satisfaction was measured using 5-point pictorial likert scale which is graded from 1 to 5 (1.Excellent.2.Good.3 Average 4.Poor. 5. Very poor).

All the plaque samples were collected and put in sterile test tubes containing thioglycolate as a transport media. They transferred to the microbiology laboratory within half an hour after rinsing for detection of bacterial counts. These samples were incubated 48-96 hours at 37°C. Number of bacterial colonies were counted by hand-held digital colony counter.

Enrollment: 84 patients

Sex: All

Ages: 5 to 8 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:• Age 5-8 years.

• No history of systemic disease.
• Patients didn't received antibiotics for at least 3 months before and during the study

Exclusion Criteria:• Children who can't expectorate completely or brush their teeth on their own.

• Fixed or removable orthodontic appliances.
• Children with intra oral abscess, oral lesions or gingival diseases.
• Parental consent was not acquired

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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84 participants in 4 patient groups

Green tea extract mouth rinse

Experimental group

Description:

group green tea extract

Treatment:

Procedure: Green tea extract mouth rinse

Garlic with lime extract mouth rinse

Experimental group

Description:

garlic with lime extract

Treatment:

Procedure: Garlic with lime extract mouth rinse

Pomegranate extract mouth rinse

Experimental group

Description:

pomegranate extract

Treatment:

Procedure: Pomegranate extract mouth rinse

Chlorhexidine mouth rinse

Experimental group

Description:

chlorhexidine

Treatment:

Procedure: Chlorhexidine mouth rinse