Evaluation of Antithrombin Deficiency in Patients of Intensive Care Unit Placed on Extracorporeal Membrane Oxygenation (ATECMO)

Rennes University Hospital

Status: Completed

Conditions: Severe Cardiac Insufficiency

Treatments: Biological: Blood sample

Study type: Observational

Funder types: Other

Identifiers

NCT04133844

35RC19_9727_ATECMO

Details and patient eligibility

About

Prospective, monocentric, non-interventional study in patients placed on extracorporeal membrane oxygenation (ECMO)

Full description

Our hypothesis is that ECMO initiation is responsible for a severe decrease of antithrombin level in a high proportion of patients who develop heparin resistance.

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any ICU patient of receiving veno-arterial extracorporeal membrane oxygenation
• Patients who have not expressed opposition to participate

Exclusion criteria

• Arterial thrombosis or progressive venous thrombosis
• Contraindication to heparin
• Constitutional deficiency in antithrombin
• Patient refusal
• Minor patient
• Protected major (safeguard justice, trusteeship and guardianship) and persons deprived of liberty

Trial design

50 participants in 1 patient group

Extracorporeal membrane oxygenation

Treatment:

Biological: Blood sample