Evaluation of Atorvastatin Treatment on Carotid Plaque.

Viatris

Status and phase

Terminated

Phase 3

Conditions

Cardiovascular Diseases

Treatments

Drug: Atorvastatin

Study type

Interventional

Funder types

Industry

Identifiers

NCT00343655

A2581152

Details and patient eligibility

About

The purpose of the study is to evaluate the effect of 18 months treatment with atorvastatin 80mg or atorvastatin 10mg on the carotid vessel plaque morphology, in particular, the effect on evident necrotic lipid rich core of the plaque in patients.

Sex

All

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Subjects with measurable carotid plaque with lipid and are eligible for statin therapy.

Exclusion criteria

Subjects at higher risk for cardiovascular disease with a screen LDL-cholesterol greater than 120 mg/dL,
Subjects currently on high dose statin, and
Subjects with contraindications for MRI or statin therapy.