Evaluation of Autogenous Demineralized Dentin Graft for Ridge Preservation With and Without Injectable Platelet Rich Fibrin

Cairo University (CU)

Status: Active, not recruiting

Conditions: Alveolar Bone Loss; Dentin Graft; Ridge Preservation

Treatments: Procedure: injectable platelet rich fibrin with demineralized dentin graft; Procedure: demineralized dentin graft

Study type: Interventional

Funder types: Other

Identifiers

NCT05437172

Shaam

Details and patient eligibility

About

Ridge preservation should be considered whenever possible after tooth extraction. Whether implant placement would be performed or for aesthetic consideration at pontic sites when conventional bridge is planned. Ridge preservation aims to maximize the bone formation accompanied with good soft tissue architecture to facilitate implant and prosthetic replacement restoring function, phonetics and aesthetics. the Aim of the study is To evaluate the bucco-lingual ridge width clinically and radiographically, height of buccal and lingual ridges of the socket after application of injectable platelet rich fibrin and autogenous dentin graft.

Enrollment: 24 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years need of at least one single rooted tooth extraction.
• Non-restorable teeth.
• Systemically healthy patients.
• Good oral hygiene, Plaque index less than 15%.
• Non-smoker or Smoking ≤ 10 cigarettes/day.
• Cooperative patients able and accept to come for follow up appointments.

Exclusion criteria

• Any interim intervention that may have affected any of the outcomes of interest.
• Pregnant and lactation females.
• Smoking ˃ 10 cigarettes/day.
• Patients reporting systemic conditions that may compromise healing or bone metabolism (eg: diabetes).
• Patients with poor oral hygiene.
• Any known allergies.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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24 participants in 2 patient groups

injectable platelet rich fibrin with deminerlized dentin graft

Experimental group

Description:

injectable platelet rich fibrin with deminerlized dentin graft for ridge preservation after teeth extraction

Treatment:

Procedure: injectable platelet rich fibrin with demineralized dentin graft

deminerlized dentin graft

Active Comparator group

Description:

deminerlized dentin graft for ridge preservation after teeth extraction

Treatment:

Procedure: demineralized dentin graft