Evaluation of Autogenous Tooth- Derived Graft With Bovine Bone For Surgical Repair of Unilateral Alveolar Cleft

Tanta University

Status: Completed

Conditions: Alveolar Cleft

Treatments: Procedure: bovine bone; Procedure: autogenous tooth graft combined with bovine bone

Study type: Interventional

Funder types: Other

Identifiers

NCT06855875

OS-4-23-2

Details and patient eligibility

About

The aim of this study is evaluation of autogenous tooth-derived graft combined with bovine bone for surgical repair of unilateral alveolar cleft .

Full description

Decalcified dentin graft is thought to be a good graft material that can substitute existing autogenous bone graft materials. It can be easily and readily available, with minimal risk of infection, minimal donor site morbidity as no vital bone is sacrificed, it can be easily shaped to fit into the bony defect and it can be used as block or in powder forms, the hypothesis is to evaluate the biological and the physical properties of both and autogenous tooth derived graft and bovine bone to increase the quality and density of newly formed bone in alveolar cleft grafting

Criteria of patient selection:

Inclusion Criteria:

Patients with unilateral alveolar clefts requiring repair. patients free from any systemic disease that may affect normal healing of bone. patients in an age 7y up to 14 y. patients have teeth to be sacrificed, as primary teeth, carious teeth, malposed teeth, supernumerary tooth& non functional tooth in the study group.

Exclusion criteria:

Bilateral alveolar clefts. Immunocompromized patients. Syndromic patients. Patients have good full set of teeth, cannot be sacrified in study group The patients grouping with unilateral alveolar cleft will be classified into two equal groups according to the grafting material used for alveolar cleft repair.

Study Group:

This will include 8 patients with unilateral alveolar cleft which will be repaired using autogenous tooth graft combined with bovine bone .

Control Group:

This will include 8 patients in whom alveolar cleft will be repaired using bovine bone .

Enrollment: 16 patients

Sex: All

Ages: 7 to 14 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with unilateral alveolar clefts requiring repair.
• patients free from any systemic disease that may affect normal healing of bone.
• patients in an age 7y up to 14 y.
• patients have teeth to be sacrificed, as primary teeth, carious teeth, malposed teeth, supernumerary tooth& non functional tooth in the study group.

Exclusion criteria

• Bilateral alveolar clefts.
• Immunocompromized patients.
• Syndromic patients.
• Patients have good full set of teeth, cannot be sacrified in study group

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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16 participants in 2 patient groups

autogenous tooth graft combined with bovine bone

Experimental group

Description:

This include 8 patients with unilateral alveolar cleft which will be repaired using autogenous tooth graft combined with bovine bone .

Treatment:

Procedure: autogenous tooth graft combined with bovine bone

bovine bone

Experimental group

Description:

This include 8 patients in whom alveolar cleft will be repaired using bovine bone .

Treatment:

Procedure: bovine bone