Evaluation of Biological Response to SARS-COV2 (COVID-19) in Patients With Pre-existing Neurological Disease or Newly Neurological Symptoms (BIO-COCO-NEUROSCIENCES)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Neurologic Manifestations; Psychiatric Manifestations; Covid19

Treatments: Other: blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT04568707

APHP200845

Details and patient eligibility

About

Patients with neurological or psychiatric symptoms or pre-existing disease will be sampled (blood for serum and DNA or saliva for DNA) at inclusion and at M6 (blood) and M12 (blood) depending on their pathology. Sampling will be done either at hospital if patient is on site for routine care or at home if no consultation is scheduled at hospital.

Enrollment: 238 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

1. Age over 18 yo

2. Patient having presented or presenting a Covid-19 infection defined by a positive PCR or a typical chest scanner of Covid-19 infection or a positive serology or a typical clinical picture in a pandemic period

3. And patient with:

   1. a neurological or psychiatric manifestation de novo during or after the Covid-19 infection and/or
   2. either a chronic neurological or psychiatric pathology

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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238 participants in 1 patient group

Covid-19 infection

Experimental group

Description:

Covid-19 infection defined by a positive PCR or a typical chest scanner of Covid-19 infection or a positive serology or a typical clinical picture in a pandemic period

Treatment:

Other: blood sample