Evaluation of Bleeding Score in Egyptian Patients With vWD Type I and Correlate it With Laboratory Parameters

Assiut University

Status: Unknown

Conditions: Von Willebrand Disease, Type 1

Treatments: Diagnostic Test: The von Willebrand Antigen level

Study type: Observational

Funder types: Other

Identifiers

NCT03915873

BS in VWD

Details and patient eligibility

About

Applying the ISTH-BAT questionnaire on Egyptian patients with type I VWD aiming to correlate the BS with the laboratory findings

Full description

The clinical phenotype of the disease is variable and tends to be mild in type 1 vWD, whereas it shows serious bleeding manifestations in types 2 and 3. Overall, the symptoms reported in vWD include easy bruising, epistaxis, gastrointestinal bleeding, excessive menstrual bleeding, postpartum haemorrhage, and excessive bleeding after surgical operation and minor wounds.However, A distinctive bleeding history is a prerequisite for the diagnosis of any bleeding disorder and should guide further laboratory investigations In an attempt to standardize the diagnostic criteria of VWD, a bleeding questionnaire and a bleeding score were developed The combination of a standardized bleeding questionnaire and a well-defined interpretation grid (for the computation of the final (BS) has been referred to as a Bleeding Assessment Tool (BAT).

Enrollment: 20 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• type 1 vWD patients
• healthy subjects with no known problem with bleeding or bruising were also recruited

Exclusion criteria

Trial design

20 participants in 2 patient groups

vWB patients

Treatment:

Diagnostic Test: The von Willebrand Antigen level

control