Evaluation of Calcinosis in Systemic Sclerosis (CALCIDERMIS)

University Hospital, Lille

Status: Completed

Conditions: Systemic Sclerosis

Treatments: Procedure: Veinous punction; Radiation: Radiography

Study type: Observational

Funder types: Other

Identifiers

NCT03340194

2016_43

2017-A01822-51 (Other Identifier)

Details and patient eligibility

About

Systemic sclerosis is a rare pathology characterized by fibrosis and vascular lesion with skin, pulmonary, digestive and cardiac localisation. Calcinosis cutis is commonly described, but its prevalence and appear few documented in literature. Moreover, this studies used clinical observation to determine presence or absence of calcification, and rarely radiography, in particular for feet localisation. In the same way, skin calcification and organ injury association appear unclear. The aim of the study is firstly to determine prevalence of calcinosis cutis, with hand and feet radiography realisation in a cohort of systemic sclerosis patient. Secondly, will be determine the correlation between calcinosis and organ injury.

Enrollment: 214 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Systemic sclerosis presenting ACR-EULAR 2013 criteria
• Given their consent
• Titulary of health insurance

Exclusion criteria

• Dermatomyositis overlap
• Pregnant or breastfeeding women
• Imprisoned person
• Refuse of consent

Trial design

214 participants in 1 patient group

Systemic sclerosis patients

Treatment:

Radiation: Radiography

Procedure: Veinous punction