Evaluation of Cardiovascular Risk Factors in Incident Dialysis Patients

University Hospital Center (CHU)

Status: Enrolling

Conditions: Chronic Kidney Disease

Treatments: Biological: Plasma osteoprotegerin level; Biological: Plasma fibroblast growth factor 23 level; Procedure: Vascular calcification score

Study type: Interventional

Funder types: Other

Identifiers

NCT02813642

UF8851

Details and patient eligibility

About

To evaluate the relationships between bone mineral markers levels at dialysis start and vascular calcification progression during a 2 year follow up

Enrollment: 400 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient who has signed the written consent form
• Patient with chronic renal failure starting dialysis therapy

Exclusion criteria

• Pregnancy
• Patient with chronic renal failure not yet on dialysis therapy

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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400 participants in 1 patient group

Cardiovascular risk evaluation

Experimental group

Description:

Measurement of plasma osteoprotegerin level, plasma fibroblast growth factor 23 level, vascular calcification score and record of cardiovascular events during the 2 year follow-up

Treatment:

Biological: Plasma osteoprotegerin level

Biological: Plasma fibroblast growth factor 23 level

Procedure: Vascular calcification score