Evaluation of Clinical Approaches to Accelerate Orthodontic Tooth Movement

Pontifícia Universidade Católica de Minas Gerais

Status: Completed

Conditions: Orthodontic Tooth Movement

Treatments: Procedure: Corticotomy; Procedure: Piezocision; Device: Control Side; Procedure: Micro-osteoperforations

Study type: Interventional

Funder types: Other

Identifiers

NCT03089996

Accelerate Tooth Movement

Details and patient eligibility

About

This study will compare the techniques of piezocision and alveolar corticotomies in accelerating orthodontic retraction movement of canines. In a second phase, this clinical trial will evaluate the effectiveness of micro-osteoperforations in accelerating the retraction of maxillary incisors.

Full description

The first phase will consist of a split-mouth study in patients who require the extraction of the first premolars to correct malocclusion. The canine will be retracted using corticotomy and piezocision surgical techniques, as well as without any intervention, being this the control side. In addition, it will be evaluated the inflammatory biomarkers present in the gingival crevicular sulcus during the dental movement, as well as data related to pain and discomfort. The second phase will evaluate the effects of micro-osteoperforations in the retraction of maxillary incisors. The following parameters will be evaluated in the upper arch: anteroposterior incisors and first molars displacement, space closure, inclination and length of central incisors.

Enrollment: 45 patients

Sex: All

Ages: 15 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient with orthodontic need for bilateral upper first premolar extraction.
• Adequate dento-oral health
• ASA I and ASA II
• Compliance with clinic visits every 2 weeks

Exclusion criteria

• History of periodontal disease
• Smokers
• Altered bone metabolism (e.g., due to anti-resorptive drug, steroid or immunosuppressant use)
• Pregnancy
• Presence of cleft or any syndrome

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 5 patient groups

Piezocision

Experimental group

Description:

Piezocision-assisted canine retraction x Control (split mouth design)

Treatment:

Procedure: Piezocision

Device: Control Side

Corticotomy

Experimental group

Description:

Corticotomy-assisted canine retraction x Control (split mouth design)

Treatment:

Procedure: Corticotomy

Device: Control Side

Piezocision x Corticotomy

Experimental group

Description:

Piezocision-assisted retraction x Corticotomy-assisted retraction (split mouth design)

Treatment:

Procedure: Corticotomy

Procedure: Piezocision

Micro-osteoperforations

Experimental group

Description:

Micro-osteoperforations-assisted upper incisors retraction

Treatment:

Procedure: Micro-osteoperforations

Control

No Intervention group

Description:

Upper incisors retraction not associated with any clinical intervention to accelerate tooth movement