Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy

Stanford University

Status: Completed

Conditions: Adenomatous Polyp of Colon; Colo-rectal Cancer; Polyp of Colon

Treatments: Procedure: Cold forcep polypectomy; Procedure: Cold snare polypectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04551001

15766-1

Details and patient eligibility

About

The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.

Full description

The details of the proposed study are as follows:

1. Experimental group: using cold forceps for polyps <=3mm of the colon

2. Control group: using cold snare for polyps <=3mm of the colon

3. Methods:

   1. Colonoscopy will be performed in the same standard of care manner as if no study was taking place.
   2. If polyps <=3mm are identified, the endoscopist is randomized to performing polypectomy with cold forcep or cold snare.
   3. After removal of the polypectomy, two biopsies are performed at the margin of the polypectomy site to identify residual lesion.
   4. The polyp as well as well as the two biopsies are reviewed by a pathologist.

Enrollment: 181 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients 18 years or older
• Polyps <=3mm

Exclusion criteria

• Pregnant
• Inflammatory bowel disease
• Polyposis syndromes

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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181 participants in 2 patient groups

Cold forcep

Experimental group

Description:

Cold forcep polypectomy performed for polyps \<=3mm.

Treatment:

Procedure: Cold forcep polypectomy

Cold snare

Experimental group

Description:

Cold forcep polypectomy performed for polyps \<=3mm.

Treatment:

Procedure: Cold snare polypectomy