Evaluation of CTA on the Assessment of Brain Death

Zhejiang University

Status: Unknown

Conditions: Brain Death

Treatments: Other: NO CTA examination; Combination Product: Combination Product

Study type: Observational

Funder types: Other

Identifiers

NCT04914039

2020-031

Details and patient eligibility

About

At present, different countries have different standards for the diagnosis of brain death, but according to the classic brain death confirmation test, it needs to be combined with transcranial Doppler, EEG, evoked potential and apnea test in clinical practice. Some patients cannot undergo a complete clinical examination and apnea test due to certain factors, and the determination of brain death is limited. The American Academy of Neurology (AAN) guidelines regard cerebral angiography as an acceptable auxiliary examination and is widely regarded as the gold standard for cerebral blood flow evaluation. CT cerebrovascular angiography (CTA) is a noninvasive and widely used examination method that can identify missing or severely reduced cerebral blood flow. However, due to limited experience and lack of sufficient evidence to prove its reliability, it is not included in the AAN A recognized auxiliary examination; there are also a large number of domestic and foreign literature reports that CTA can be used as a new confirmation test for clinical judgment of brain death.

This study aims to explore the value of CTA in the judgment of patients with brain death.

Enrollment: 63 estimated patients

Sex: All

Ages: 12 to 72 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Recruiting, no definite

Exclusion criteria

• Recruiting, no definite

Trial design

63 participants in 2 patient groups

CTA examination

Description:

CTA examination group for suspected brain death

Treatment:

Combination Product: Combination Product

Confirmed

Description:

Confirmed group for brain death

Treatment:

Other: NO CTA examination