Evaluation of Daily HemoDialysis at Low Dialysate Flow in Patients Previously Treated With Conventional Hemodialysis (HDQ200)

Association Pour L'utilisation Rein Artificiel Région Lyonnaise

Status

Terminated

Conditions

End Stage Renal Disease

Treatments

Other: Daily hemodialysis at low dialysate flow

Study type

Interventional

Funder types

Other

Identifiers

NCT01845012

2012-A00307-36

Details and patient eligibility

About

HDQ 200 is an interventional multicenter study. This is a before-and-after design in which the patient is his own control. The main objective of the study is to determine the percentage of success of a procedure of daily hemodialysis at low dialysate flow. All patients treated with conventional hemodialysis, for at least 3 months and clinically stable, can be included in the study. Their 3 months data prior to inclusion is collected retrospectively. These 3 months of conventional hemodialysis are the reference period. Patients are then treated with daily hemodialysis at low dialysate flow for 3 months. During this 3 months period, the same data as during the period of conventional hemodialysis are collected prospectively.

Enrollment

2 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18 years
Patients who give voluntary signed informed consent
Patients affiliated with the French universal health care system or similar
For women of childbearing potential: serum or urine negative pregnancy test
Patients treated with conventional hemodialysis (3 times 4h to 5h per week at at least a dialysate flow rate of 500 ml/min) for at least 3 months and clinically stable (investigator assessment)
Bipuncture patients (or with double lumen central venous catheter) with stable vascular access and easy to puncture
Patients willing to be treated with daily hemodialysis at low dialysate flow during the study period (6 times 2h to 2h30 per week at a dialysate flow rate of 200 ml/min in order that the total duration of weekly dialysis is equivalent to the duration of weekly dialysis during the last 3 months of conventional hemodialysis)

Exclusion criteria

Pregnant women or women who could become pregnant during the study (planned pregnancy within 3 months)
Patients not affiliated with the French universal health care system
Minor patients
Patients who are protected adults according to the terms of the law (French public health laws).
Refusal to give consent
Patients simultaneously participating in another trial that may interfere with the study results