Evaluation of Daily Hemodialysis With Low Dialysate Flux in Unscheduled Patients With Kidney Injury Admitted to Hemodialysis (EQUODIA)

Centre Hospitalier Departemental Vendee

Status

Terminated

Conditions

Acute Kidney Injury

Kidney Failure, Chronic

Treatments

Device: Conventional triweekly high-flow hemodialysis

Device: Hemodialysis with low dialysate flow

Study type

Interventional

Funder types

Other

Identifiers

NCT03963960

CHD039-19

Details and patient eligibility

About

The objective of the EQUODIA study is to evaluate the hemodynamic stability of hemodialysis with low dialysate flow in patients requiring emergency hemodialysis in the context of acute kidney injury or unscheduled end-stage renal disease, not in intensive care, compared to conventional triweekly high-flow hemodialysis.

Short daily hemodialysis has excellent hemodynamic tolerance, which has already been confirmed by clinical experience. This modality, commonly used in the patient's home through new machines allowing a low dialysate flow purification technique, can prove to be an innovative, effective and safe alternative for patients admitted for hemodialysis in an unscheduled situation (acute kidney injury, unscheduled end-stage renal disease not followed).

Up to now, no studies have evaluated the use of short daily hemodialysis with low dialysate flow in patients with acute kidney injury or unscheduled end-stage renal disease, requiring the initiation of emergency extra-renal purification.

Enrollment

13 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male or Female 18 years of age or older
Patient requiring unscheduled hemodialysis for end-stage renal disease or acute kidney injury
Patient able to understand the protocol
Patient who has agreed to participate in the study and has given express oral consent
Patient affiliated to a social security system

Exclusion criteria

Patient with more than one dialysis session
Intensive care patient (need for vasoactive amine infusion, non-invasive ventilation, assisted ventilation)
Patient participating in interventional clinical research involving a drug/medical device
Patient under guardianship, curator, deprived of liberty
Pregnant or breastfeeding patient, or with the ability to procreate without effective contraception
Patient refusing to participate
Patient unable to understand the protocol and/or give express oral consent