Evaluation of Deposits on Contact Lenses Worn Daily Wear

Alcon

Status: Completed

Conditions: Refractive Error

Treatments: Device: Balafilcon A contact lenses (PureVision); Device: Etafilcon A contact lenses (Acuvue2)

Study type: Interventional

Funder types: Industry

Identifiers

NCT00725153

MS-006

Details and patient eligibility

About

The purpose of this study was to measure front surface deposits on contact lenses when worn for ten hours.

Enrollment: 55 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years or older.
• Visual acuity correctable to 20/30 (Snellen) or better in each eye at distance with contact lenses.
• Successfully wearing hydrogel or silicone hydrogel contact lenses prior to enrollment in the study.
• Other protocol-defined inclusion criteria may apply.

Exclusion criteria

• Evidence or history of keratitis (dendritic keratitis); viral disease of the cornea and/or conjunctiva; acute bacterial disease of the cornea and/or conjunctiva and/or eyelids; infection of the eye; and/or fungal disease of the eye.
• One functional eye or a monofit lens.
• Ocular conditions such as active acute blepharitis, conjunctival infections, and iritis.
• Any slit-lamp finding score of (1) at the Screening Visit as defined in protocol.
• Use of concomitant topical ocular prescription or over-the-counter (OTC) ocular medications.
• History of seasonal allergies with significant ocular side effects which may have an adverse impact on contact lens wear.
• Other protocol-defined exclusion criteria may apply.

Trial design

55 participants in 2 patient groups

PureVision/Acuvue 2

Other group

Description:

PureVision contact lenses worn first, with Acuvue 2 contact lenses worn second. Both products worn for 10 hours each.

Treatment:

Device: Etafilcon A contact lenses (Acuvue2)

Device: Balafilcon A contact lenses (PureVision)

Acuvue 2/PureVision

Other group

Description:

Acuvue 2 contact lenses worn first, with PureVision contact lenses worn second. Both products worn for 10 hours each.

Treatment:

Device: Etafilcon A contact lenses (Acuvue2)

Device: Balafilcon A contact lenses (PureVision)