Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity

Federal University of Uberlandia

Status: Unknown

Conditions: Dentine Hypersensitivity; Dentin Sensitivity; Hypersensitivity Dentin; Dentin Hypersensitivity

Treatments: Drug: UltraEZ; Drug: Enamelast

Study type: Interventional

Funder types: Other

Identifiers

NCT03076944

CAAE:60751416.1.0000.5152

Details and patient eligibility

About

The aim of this study is through a double blind randomized clinical trial, evaluate the effectiveness of different clinical protocols in the reduction of dentin hypersensitivity. The desensitization approach (single agent or associated agents) and the long-term effectiveness (baseline, 1 week, 2 weeks, 4 weeks, 12 weeks and 24 weeks) will be evaluated. Data will be collected, tabulated and submitted to statistical analysis.

Full description

Dentin hypersensitivity is characterized as an acute and short-term pain with multifactorial etiology. This condition is a clinical challenge due to the different treatment protocols available. Therefore, the aim of this study is through a double blind randomized clinical trial, evaluate the effectiveness of different clinical protocols in the reduction of dentin hypersensitivity. Thirty-two patients with dentin hypersensitivity in at least three teeth will be selected.The teeth will be randomly divided into two different groups according to the desensitization approach (single agent with neural action; single agent with obliterating action; associated technique (neural and obliterator agents). The dentin hypersensitivity level will be evaluated immediately after desensitization and after 1, 2, 4,12 and 24 weeks. Data will be collected, tabulated and submitted to statistical analysis.

Enrollment: 32 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy individuals
• Both genres, interested in the treatment of Dentin Hypersensitivity
• Patients with all teeth in their mouth
• Patients who have at least three teeth with Dentin hypersensitivity in different quadrants
• Good oral hygiene

Exclusion criteria

• Caries or unsatisfactory restorations
• Presence of periodontal disease and or parafunctional habits
• Cracks or enamel fractures
• Extensive or unsatisfactory restorations
• Recent restorations involving the labial surface
• Pulpitis
• Dentures
• Orthodontics
• Smokers
• Pregnant women
• Gastroesophageal disease presence
• Uncontrolled systemic disease
• Severe bruxism
• Constant use of analgesic
• Allergic response to dental products

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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32 participants in 3 patient groups

Neural agent

Active Comparator group

Description:

UltraEZ. Prophylaxis of the teeth; an application every 48 hours; 4 sessions

Treatment:

Drug: UltraEZ

Obliterator agent

Active Comparator group

Description:

Enamelast. Prophylaxis of the teeth; an application every 48 hours; 4 sessions

Treatment:

Drug: Enamelast

Associative approach

Active Comparator group

Description:

UltraEZ and Enamelast. Prophylaxis of the teeth; an application every 48 hours; 4 sessions. In each session, fistly the UltraEZ (neural agent) will be applied and after the Enamelast (obliterator agent.)

Treatment:

Drug: Enamelast

Drug: UltraEZ