Evaluation of Diaphragmatic Function After Bi-pulmonary Transplantation (DIATRIB)

Centre Chirurgical Marie Lannelongue

Status: Unknown

Conditions: Lung Transplant, Diaphragmatic Function

Study type: Observational

Funder types: Other

Identifiers

NCT03977597

2018-A02418-47

Details and patient eligibility

About

A current complication after lung transplantation is diaphragmatic dysfunction. These dysfunction result to several factors: duration of mechanical ventilation, chest tube, atelectasis, denutrition, phrenic nerve injury during surgical dissection... Only monocentric and retrospective studies collected diaphragmatic paralysis after lung transplant are published. The incidence of diaphragmatic paralysis in post-operative lung transplantation varies from 3.2% to 16.8%.

The main hypothesis of the study is to defined the incidence of diaphragmatic dysfunction in post-operative lung transplantation.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults (≥ 18 years old)
• Admitted for intensive care that can be spontaneously ventilated after bi- pulmonary transplantation

Exclusion criteria

• Minor patient
• Ventilated patients less than 24 hours
• patients in controlled ventilation