Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

University of Verona

Status: Unknown

Conditions: Asthma; Rhinitis

Treatments: Other: regular treatment

Study type: Observational

Funder types: Other

Identifiers

NCT00952835

AOV-1716

Details and patient eligibility

About

In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology.

The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.

Full description

Each patients will be evaluated by spirometry and then he will undergo exercise challenge in order to evaluate exercise-induced bronchoconstriction as a marker of asthma control. The test of the challenge will be correlate with childhood Asthma control test score,levels of control (GINA classification)and the different markers of airway inflammation and atopy.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 5+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient with asthma and rhinitis

Exclusion criteria

• age <5 years
• chronic respiratory diseases

Trial design

1,000 participants in 1 patient group

asthma and rhinitis control

Treatment:

Other: regular treatment