Evaluation of Drainable Volume Measurements During VA-ELS

Maastricht University Medical Centre (MUMC)

Status: Unknown

Conditions: Heart Arrest

Treatments: Device: VA-ELS pump speed variations

Study type: Interventional

Funder types: Other

Identifiers

NCT02326506

NL49011.000.14

Details and patient eligibility

About

Veno-arterial extracorporeal life support (VA-ELS) is used to support patients with acute cardiac failure. In that context, sufficient drainable venous volume is crucial for reliable and adequate support. To date, no reliable measurement method exists to monitor drainable volume adequately. Furthermore, it is still unresolved how to diagnose adequate cardiac recovery.

Previous (pre)clinical studies showed that the calculation of the dynamic filling index may provide a valuable parameter to monitor the drainable volume in patients supported by VAELS. In addition, a case report showed that measurement of the dynamic filling index could successfully be used to estimate cardiac recovery in a single patient supported by VA-ELS in the ICU.

This study will assess the dynamic filling index as a representation for drainable volume and cardiac recovery using standard recorded perfusion data in patients supported by VA-ELS

Enrollment: 10 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Written informed consent of the relative(s) or legal representative(s)
• Supported by VA-ELS at the ICU
• >18 years

Exclusion criteria

• Pregnancy

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Pump speed variation

Experimental group

Description:

VA-ELS pump speed variations

Treatment:

Device: VA-ELS pump speed variations