Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers

Dialpha

Status: Unknown

Conditions: Weight Loss

Treatments: Dietary Supplement: Cashew apple extract (Cashewin); Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT02493140

2015-A00160-49

Details and patient eligibility

About

The purpose of this study is to assess the efficacy and safety of a cashew apple extract on weight management and associated metabolic risk factors in overweight/obese volunteers, versus placebo, after 12 weeks of treatment.

Enrollment: 66 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 27 ≤ BMI ≤ 35 kg/m²
• Abdominal obesity
• Acceptance to adhere to diet and physical activity recommendations while maintaining global lifestyle habits
• Stable body weight (<5% variation) within the last 3 months prior to screening

Exclusion criteria

• Allergy to nuts and products thereof and allergy to mango fruit
• Type I or II diabetes
• Smokers
• Severe chronic diseases
• History of bariatric surgery and eating disorders
• Use of weight management products or medications which could affect nutrients absorption, lipids or carbohydrates metabolism

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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66 participants in 2 patient groups, including a placebo group

Cashew apple extract (Cashewin)

Active Comparator group

Treatment:

Dietary Supplement: Cashew apple extract (Cashewin)

Placebo

Placebo Comparator group

Treatment:

Dietary Supplement: Placebo