Evaluation of Energy Expenditure, Body Composition and Recovery Rates in Children With Severe Acute Malnutrition

Aga Khan University

Status: Completed

Conditions: Malnutrition; Children

Treatments: Behavioral: Nutrition education; Dietary Supplement: RUTF

Study type: Interventional

Funder types: Other

Identifiers

NCT01144806

1400-Ped-ERC-09

Details and patient eligibility

About

This project is being conducted with an aim to find out energy expenditure, body composition and recovery rates in children with severe acute malnutrition (SAM) receiving community-based nutritional rehabilitation therapy

Full description

Objectives

1. To assess energy expenditure and body composition by stable isotope techniques in children with Severe Acute Malnutrition
2. To evaluate the potential usefulness of body composition assessment as a predictor of outcome in children with SAM, based on stable isotope technique and multi-frequency bioelectrical impedance analysis (BIA)

Inclusion criteria

• Parents of children of age 6 months to 3 years
• Resident of study area

Exclusion criteria

• Children with congenital malformations
• Chronic debilitating illnesses
• Refusal by parents to enroll in study

Enrollment: 60 patients

Sex: All

Ages: 6 months to 3 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parents of children of age 6 months to 3 years
• Resident of study area

Exclusion criteria

• Children with congenital malformations
• Chronic debilitating illnesses
• Refusal by parents to enroll in study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

---

60 participants in 2 patient groups

Group 1

Active Comparator group

Description:

Parent/care givers of children with severe malnutrition in enrolled in this group will be given nutrition education using the principles of infant and young child feeding (IYCF) and dietary diversification

Treatment:

Behavioral: Nutrition education

Group 2

Active Comparator group

Description:

Ready to use therapeutic food (RUTF / PlumpyNut)will be provided to parent/care givers of children with severe malnutrition in enrolled in this group

Treatment:

Dietary Supplement: RUTF