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Evaluation of Femoral Cartilage Thickness After Treadmill and Tartan Track Walking

P

Pamukkale University

Status

Not yet enrolling

Conditions

Knee Osteoarthritis

Treatments

Other: walking

Study type

Interventional

Funder types

Other

Identifiers

NCT05316792
PamukkaleU-Simsek-002

Details and patient eligibility

About

The aim of this study is to measure and compare the femoral cartilage deformation after walking on the treadmill and tartan floor in patients with knee osteoarthritis (OA) and healthy volunteers.

Full description

The investigators will recruit 30 patients who will be applied to Physical Medicine and Rehabilitation outpatient clinic and diagnosed with knee OA according to American College of Rheumatology (ACR) criteria and 30 healthy volunteers matched for age and gender. The sociodemographic characteristics and detailed history of the patients included in the study will be questioned and recorded. After a detailed physical examination of all patients, weight and height will be measured, and body mass indexes (BMI) will be calculated. Participants' physical activity levels will be determined based on the World Health Organization's Global Physical Activity Questionnaire. This questionnaire has been reported to provide a valid and reliable estimate of physical activity, Turkish validity and reliability have been established.

A repeated measures design will be used in which healthy volunteers and patients with knee OA all complete all loading conditions (30min walking on the treadmill and tartan floor). For this, each group (healthy volunteers and knee OA patients) will first walk on the treadmill and then do tartan ground walking 1 week later. Femoral articular cartilage thickness before and immediately after walking will be measured with portable ultrasonography (USG) with a telemedicine feature.

Upon arrival at the treatment unit or area of the tartan track, participants will sit on a treatment table with their knees fully extended for 30 minutes to minimize the effects of previous activity on cartilage. All sessions will be completed at the same time of day to reduce daily variations in cartilage thickness. The dominant leg will be defined as the self-reported limb that the participant chooses to use to kick a ball. All post-load USG procedures will be achieved within 5 minutes after the loading condition. 3 images will be taken from each participant.

Two separate evaluators will measure to determine the reliability among the measurers.

To equalize the loading, the speed at which each participant walks on the treadmill in 30 minutes will be determined by the pedometer as a brisk walking speed (5 km/h). Again, each participant will walk on the tartan floor with a pedometer and walk for 30 minutes at an equal distance at the same pace as on the treadmill. The pedometer will give a warning when it is below or above the desired speed.

Enrollment

60 estimated patients

Sex

All

Ages

40+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Be over 40 years old
  • Having been diagnosed with knee OA according to the ACR diagnostic criteria
  • Being diagnosed with stage 1-2 knee OA according to the Kellgren-Lawrence staging criteria

Exclusion criteria

  • Having a musculoskeletal or systemic disease that will prevent the exercise
  • History or symptoms of lower extremity surgery, ligament injury, balance disorder, lower extremity injury in the last 6 months
  • Presence of psychiatric or neurological disease affecting cooperation, cognitive and neurological functions

Trial design

Primary purpose

Other

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

60 participants in 2 patient groups

knee osteoarthritis
Active Comparator group
Description:
In patients with knee osteoarthritis, the thickness of the femoral articular cartilage will be measured with portable USG before and immediately after walking.
Treatment:
Other: walking
healthy volunteers
Active Comparator group
Description:
Femoral articular cartilage thickness will be measured with portable USG before and immediately after walking in healthy volunteers.
Treatment:
Other: walking

Trial contacts and locations

0

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Central trial contact

Ayse Simsek, m.d.

Data sourced from clinicaltrials.gov

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