Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery (fluidresponse)

Ankara City Hospital

Status: Enrolling

Conditions: Coronary Artery Bypass Surgery Patients; Fluid Therapy; Lung Recruitment Maneuver

Study type: Observational

Funder types: Other

Identifiers

NCT06249568

E2-23-3460

Details and patient eligibility

About

Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass surgery, it is useful to predict fluid responsiveness after sternotomy in coronary artery bypass surgery patients ventilated with 6 ml/kg PBW (ideal body weight). We aimed to reveal the sensitivity and specificity of PPV and SVV changes by applying a lung opening maneuver.

Full description

In order to evaluate the fluid deficit in patients undergoing coronary artery bypass surgery, researchers will measure stroke volume index, cardiac index and mean arterial pressure while the patients are in the lima position.

Then researchers will perform a lung opening maneuver (30mmHg for 30 seconds) and measure again.

researchers will measure again after the values return to normal. researchers will give patients balanced fluid at 3ml/kg and record their values.

Can researchers predict fluid response with lung opening maneuver?

Enrollment: 45 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Inclusion Criteria:
• 1-ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia
• Exclusion Criteria:
• 1. Be younger than 18 years old, be over 80 years old
• 2. Patients with an ASA score greater than 3
• 3. EF<40%
• 4. Those with contraindications to anesthetic drugs
• 5. Patients with BMI>30
• 6. Patients who did not want to participate in the study
• 7. Right ventricular dysfunction
• 8. COPD(Chronic obstructive pulmonary disease)
• 9. Bullous lung disease
• 10. Moderate to severe PHT
• 11. Severe kidney or liver disease
• 12. Patients with hemodynamic instability in the perioperative period
• 13. Pregnancy

Trial design

45 participants in 1 patient group

patients who will have coroner arter bypass surgeon

Description:

Patients undergoing coronary artery bypass surgery will be eliminated if there are exclusion criteria. Patients who do not have exclusion criteria will be included in the study if they agree to volunteer.