Evaluation of Fractalkine and Its Receptor in Peri-implantitis

Kubilay BARIŞ

Status: Enrolling

Conditions: Peri-implantitis

Treatments: Procedure: Er:YAG laser decontamination; Procedure: Subgingival debridement; Procedure: Diyot laser decontamination

Study type: Interventional

Funder types: Other

Identifiers

NCT06685523

KU-DHF-KB-01

Details and patient eligibility

About

In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.

Enrollment: 100 estimated patients

Sex: All

Ages: 40 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Probing depth of 4-6 mm, bone loss of at least 2 mm on X-ray and presence of inflammatory symptoms in soft tissue
• No systemic disease that may affect the outcome of the treatment
• Patients with healthy periodontium or patients with completed periodontal treatment
• Individuals at least 6 months after prosthesis loading on the implant
• Individuals who do not require further surgery for the treatment of peri-implantitis
• Implants with at least 2 mm keratised gingiva
• Individuals aged 40-60 years

Exclusion criteria

• Individuals undergoing radiation therapy
• Individuals who smoke and drink alcohol
• Individuals in pregnancy or lactation
• Individuals who have received antibiotic treatment in the last three months
• Individuals with parafunctional habits

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 4 patient groups

Group healty

No Intervention group

Mechanical debridement group

Experimental group

Treatment:

Procedure: Subgingival debridement

Er:YAG laser applied group

Experimental group

Treatment:

Procedure: Er:YAG laser decontamination

Diyot laser applied group

Experimental group

Treatment:

Procedure: Diyot laser decontamination