Evaluation of Glucose Monitoring Methods: Characterizing Glycemic Control in Subjects With Diabetes
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About
Evaluate the usefulness of continuous glucose monitoring devices in terms of their ability to identify periods throughout the day when glucose varies significantly.
Full description
Many CGM systems use a surrogate for blood glucose--tissue glucose or interstitial glucose. Interstitial fluid (ISF) is the medium for these approaches. A physiological lag in ISF glucose relative to capillary blood glucose has been noted, probably due to relatively low blood perfusion at the sampling site. 9 This physiological lag can result in an accuracy error, manifesting as a significant bias between blood and tissue glucose, particularly during periods of rapid glucose change. This lag error might be particularly meaningful when glucose is rapidly dropping towards hypoglycemia.
Enrollment
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Inclusion criteria
- adult
- A1c >7.4 within last 4 months
- type 1 or 2 diabetes treated with basal/bolus insulin
Exclusion criteria
- under 18 years of age
- unable to read/write english
- allergy to adhesives
- employee of CGM company
Trial design
16 participants in 1 patient group
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Data sourced from clinicaltrials.gov
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