Evaluation of Green Tea for Improving Blood Lipid Profile

Taipei Medical University

Status: Active, not recruiting

Conditions: Hypercholesterolemia

Treatments: Dietary Supplement: Intervention; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06992765

lin5611_2

Details and patient eligibility

About

The objects of this study are to evaluate the effects of the "Heysong japanese green tea" on the human subjects who are dyslipidemia. In this trial, 40 healthy subjects whose ages are 18~65 years old (20 for placebo and 20 for experimental) will be included. The total experiment will be 16 weeks and the intervention period will be 12 weeks, within which, at wk 0, 2, 8, 14 and 16, serum triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) values would be measured. Urine/feces samples and anthropometric data will also be acquired. The results will be analyzed according to the methods published by the Ministry of Health and Welfare of Taiwan Food and Drug Administration.

Enrollment: 38 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male and female. Age between 18-65 years old.

• Those who have been assessed as dyslipidemia by a family physician but have not yet required medication. The following measurement values were used as evaluation criteria:

  1. Hypercholesterolemia: plasma total cholesterol (TC) >200 mg/dL;
  2. Mixed hyperlipidemia: plasma total cholesterol (TC) >200 mg/dL , triglyceride (TG) >200 mg/dL;
  3. Hypertriglyceridemia: plasma triglyceride (TG) >200 mg/dL, and high-density lipoprotein cholesterol (HDL-C) < 35 mg/dL or TC/HDL-C >5.

Exclusion criteria

• Pregnant, breastfeeding, menopausal women.
• Take any drugs or supplements that can affect blood lipid levels 2 weeks before or during the experiment.
• People with intolerance to caffeine or green tea.
• People who take drugs for chronic diseases.
• People who smoke or drink alcohol.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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38 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

2 bottles of light green tea daily containing totally 108 mg of catechin

Treatment:

Dietary Supplement: Placebo

Intervention

Experimental group

Description:

2 bottles of light green tea daily containing totally 684 mg of catechin

Treatment:

Dietary Supplement: Intervention