Evaluation of Healing Process After Laser Asissted Gingivectomy Techniques

Tokat Gaziosmanpasa University

Status: Completed

Conditions: Gingival Enlargement

Treatments: Procedure: Resective Gingival Surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT04304391

TOGUGKARA

Details and patient eligibility

About

Objective: The aim of this study was to evaluate and determine clinical and biochemical comparison of 3 different methods including Er:YAG laser, diod laser, and conventional techniques.

Method: This study was conducted on 32 female, 13 male, a total of 45 individuals (study group patients) with an indication of resective gingival surgery in the anterior region of the maxillar anterior regions and 11 female, 4 men, a total of 15 individuals (negative control group patients) with a healthy gingiva. Clinical periodontal parameters, gingival crevicular fluid (GCF) KGF-2 and VEGF-A levels and gingival temperature levels were recorded before the investigation and during operations with 3 different techniques, gingival temperature was measured. Gingival temperature and epithelization levels in 3, 7, 14 and 21 days; GCF KGF-2 and VEGF-A levels in 14 and 21 days and pain levels between 1-7 days of post-operative healing process were evaluated. Preoperative anxiety and postoperative satisfaction were evaluated through questionnaires

Full description

Objective: The aim of this study was to evaluate and determine clinical and biochemical comparison of 3 different methods including Er:YAG laser, diod laser, and conventional techniques commonly used in resective gingival surgeries in terms of preoperative anxiety, postoperative satisfaction, epithelization, gingival temperature, inflammation and pain levels in post-operative healing process.

Method: This study was conducted on 32 female, 13 male, a total of 45 individuals (study group patients) with an indication of resective gingival surgery in the anterior region of the maxillar anterior regions and 11 female, 4 men, a total of 15 individuals (negative control group patients) with a healthy gingiva. Clinical periodontal parameters, gingival crevicular fluid (GCF) KGF-2 and VEGF-A levels and gingival temperature levels were recorded before the investigation and during operations with 3 different techniques, gingival temperature was measured. Gingival temperature and epithelization levels in 3, 7, 14 and 21 days; GCF KGF-2 and VEGF-A levels in 14 and 21 days and pain levels between 1-7 days of post-operative healing process were evaluated. Preoperative anxiety and postoperative satisfaction were evaluated through questionnaires

Enrollment: 60 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• systemically healthy individuals
• the existence of at least 20 functioning teeth,
• the existence of chronic inflammatory gingival enlargement

Exclusion criteria

• pregnancy/lactation,
• drug use,
• previous periodontal therapy within 6 months

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 4 patient groups

Group A

Experimental group

Description:

Conventional Gingivectomy:Technique is performed with conventional surgical instruments.

Treatment:

Procedure: Resective Gingival Surgery

Group B

Experimental group

Description:

Diode Laser Assisted Gingivectomy: Technique is performed with using diode laser.

Treatment:

Procedure: Resective Gingival Surgery

Group C

Experimental group

Description:

Er:YAG Laser Assisted Gingivectomy: Technique is performed with using Er:YAG laser.

Treatment:

Procedure: Resective Gingival Surgery

Group D

No Intervention group

Description:

Negative Control Group