Evaluation of Heart Status in Patients of Beta Thalassemia Using Echocardiogram

Nanfang Hospital, Southern Medical University

Status: Enrolling

Conditions: Beta Thalassemia

Treatments: Diagnostic Test: Echocardiogram and Hematological Analysis

Study type: Observational

Funder types: Other

Identifiers

NCT04929574

Heart-Beta thalassemia

Details and patient eligibility

About

Heart failure from myocardial iron deposition is a severe complication for patients with transfusion-dependent beta thalassemia . Increased cardiac iron content impacts the contractility of cardiomyocytes and can also lead to myocarditis, pericarditis, and arrhythmias. The severity of cardiac dysfunction depends on the amount of iron deposited in the myocardium.Echocardiogram is used as noninvasive method to observe heart status. The objective of this study is to evaluate the heart status in patients of Beta Thalassemia from southern China.

Enrollment: 1,200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with beta-thalassemia

Exclusion criteria

• Iron deficiency anemia

Trial design

1,200 participants in 1 patient group

beta thalassemia patients

Treatment:

Diagnostic Test: Echocardiogram and Hematological Analysis