Evaluation of Hemodynamic Changes Using Different IAP for LC Under General Anesthesia

Superior University

Status: Active, not recruiting

Conditions: Laparocele

Treatments: Diagnostic Test: Medium Pressure Pneumoperitoneum; Diagnostic Test: Low Pressure Pneumoperitoneum

Study type: Observational

Funder types: Other

Identifiers

NCT07055074

MSAHSW/Batch-Fall23/918

Details and patient eligibility

About

This cross-sectional observational study aims to evaluate the hemodynamic changes induced by different intra-abdominal pressures (IAP) during laparoscopic cholecystectomy under general anesthesia.

Full description

Laparoscopic cholecystectomy, a minimally invasive surgery, requires CO₂ insufflation to create a pneumoperitoneum, which alters intra-abdominal pressure and can affect cardiovascular and respiratory stability. This study assesses how varying IAP levels (8-10 mmHg, 12-14 mmHg, and 15-20 mmHg) influence heart rate, blood pressure, oxygen saturation, respiratory rate, and end-tidal CO₂.

Enrollment: 150 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing laparoscopic cholecystectomy under general anesthesia
• Age between 18-60 years
• ASA physical status I-II
• Provided informed consent

Exclusion criteria

• History of cardiovascular or respiratory diseases or other Significant comorbidities affecting hemodynamic stability.
• Pregnant patients
• Allergies to anesthetic agents

Trial design

150 participants in 2 patient groups

Low Pressure Pneumoperitoneum

Treatment:

Diagnostic Test: Low Pressure Pneumoperitoneum

Medium Pressure Pneumoperitoneum

Treatment:

Diagnostic Test: Medium Pressure Pneumoperitoneum