Evaluation of Hereditary Cancer Educational Videos

M.D. Anderson Cancer Center

Status: Active, not recruiting

Conditions: Hereditary Cancer

Treatments: Behavioral: Interview Study; Behavioral: Survey Study

Study type: Observational

Funder types: Other

Identifiers

NCT06157801

NCI-2023-10074 (Other Identifier)

2023-0654

Details and patient eligibility

About

To learn if educational videos can help participants be more informed about hereditary cancers (ones that run in the family).

Full description

Primary Objective

Determine the impact of educational videos on:

• Participant's hereditary cancer knowledge.
• Participant's confidence to share hereditary cancer information with family members.

Secondary Objective

• Determine impact of educational videos on participant's confidence to undergo hereditary cancer screening.
• Identify opportunities to tailor and improve the educational video's content, style, and understandability per participant preferences and feedback.

Enrollment: 43 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Participants of The Harris Health System Lyndon B. Johnson (LBJ) Hospital outpatient oncology clinics (i.e., Gynecologic Oncology, Medical Oncology).
2. 18 years of age or older.
3. Speaks and/or reads English or Spanish.
4. Has a pathogenic or likely pathogenic variant (mutation) in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM on germline genetic testing.
5. Has a documented genetic testing results disclosure encounter (i.e. telephone call, follow-up appointment).

Exclusion criteria

1. No longer receives outpatient care at LBJ Hospital at time of recruitment.
2. Has only a variant of uncertain significance in BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, and/or EPCAM.
3. Has only a pathogenic or likely pathogenic variant in gene other than BRCA1, BRCA2, MLH1, MSH2, MSH6, PMS2, or EPCAM.
4. Is unwilling, unable, or requires a legally authorized representative to provide informed consent.

Trial design

43 participants in 2 patient groups

Interview Study

Description:

In the interview study, participants will watch the video, then complete an interview. This will take about 50 minutes.

Treatment:

Behavioral: Interview Study

Survey Study

Description:

In the survey study, participants will complete a survey about your education and complete a quick test about your knowledge of hereditary cancer. Participants will then watch the video. complete another survey similar to the one before the video. This should take about 30 minutes.

Treatment:

Behavioral: Survey Study