Evaluation of Inspiratory Muscle Strength Early After Coronary Artery Bypass

Hospital de Clinicas de Porto Alegre

Status and phase: Completed; Phase 3

Conditions: Coronary Artery Disease

Treatments: Other: In Hospital Cardiopulmonary Rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT00873028

P1CRh

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of a 6-day postoperative in hospital cardiopulmonary rehabilitation program on inspiratory muscle strength and its potential association with improved functional capacity after coronary artery bypass grafting surgery.

Full description

Eligible patients were randomized to a cardiopulmonary rehabilitation program (Rehab; n = 10) or to usual care (Control; n = 10). The randomization was done by the Graphpad StatMate computerized program. Those patients assigned to Control were followed by their own physicians, received routine nursing assistance, were visited daily by the one of the investigators (CPM), but were not exposed to any specific respiratory or motor physical intervention. Those randomized to Rehab received the same medical and nursing care, but followed a structured physical therapy program twice a day.

Enrollment: 20 patients

Sex: All

Ages: 21 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Previous history of more than one vessel coronary artery disease
• Lifelong abstinence from tobacco
• Formal indication for CABG

Exclusion criteria

• Patients older than 75 years of age
• Chronic renal failure (dialysis for more than 3 months)
• Unstable angina in the 48 hours prior to CABG
• Moderate or severe valve disease
• Complex cardiac arrhythmia's
• Stroke
• Inability to exercise the lower limbs
• Previous pulmonary disease (forced vital capacity [FVC] < 80% of predicted and/or forced expiratory volume in 1 s [FEV1] < 70% of predicted)
• Previous history of asthma.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

1

Experimental group

Treatment:

Other: In Hospital Cardiopulmonary Rehabilitation

2

No Intervention group

Description:

Those patients assigned to Control were followed by their own physicians, received routine nursing assistance, were visited daily by the one of the investigators (CPM), but were not exposed to any specific respiratory or motor physical intervention.