Evaluation of Intestinal Lesions and Disease Activity in Inflammatory Bowel Disease Based on 18F-FAPI PET Imaging (IBD，18F-FAPI)

Army Medical University of People's Liberation Army

Status

Not yet enrolling

Conditions

Disease Activity

Inflammatory Bowel Disease (IBD)

FAPI

Treatments

Diagnostic Test: 18F-FAPI PET Imaging

Study type

Observational

Funder types

Other

Identifiers

NCT06945549

2025137

Details and patient eligibility

About

The goal of this observational study is to evaluate the role and effect of 18F-FAPI PET imaging in the identification of intestinal lesions and the assessment of disease activity in inflammatory bowel disease. The main question it aims to answer is:

Can 18F-FAPI PET imaging effectively identify intestinal lesions in inflammatory bowel disease and accurately assess disease activity? Colonoscopy, enhanced abdominal CT, and 18F-FAPI intestinal imaging were completed within 1 week, and major adverse outcomes (MAO) were followed up 12 months after enrollment.

Last updated on March 25, 2025

Enrollment

30 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients diagnosed with IBD according to clinical, imaging, endoscopic, and histopathological criteria;
Patients ≥18 years old;
18F-FAPI PET/CT intestinal imaging, conventional endoscopic and enhanced CT were performed within 1 week;
Intestinal segment matching was evaluated by endoscopy and imaging;
Patients voluntarily participate and sign informed consent.

Exclusion criteria

Pregnant or lactating patients;
Imaging images are of poor quality and cannot be used for diagnosis and evaluation;
Patients with contraindications for endoscopic or CT examination.