Evaluation of Intestinal Parasites in Patients With Intestinal Cancer in Sohag, Egypt.

Sohag University

Status: Enrolling

Conditions: Intestinal Parasites in Patients With Intestinal Cancer

Treatments: Diagnostic Test: stool examination

Study type: Observational

Funder types: Other

Identifiers

NCT05850884

Soh-Med-23-04-24MS_

Details and patient eligibility

About

This study aims to evaluate the intestinal parasitic infections in patients with intestinal cancer in comparison to non-cancer individuals

Full description

Intestinal parasitic infections continue to be characterized as a significant cause of morbidity worldwide, and according to World Health Organization (WHO) statistics, more than a quarter of the world's population, mostly in developing countries, are infected Acquisition of infection, clinical severity, and outcome of a parasitic disease depend on innate and acquired host immunity as well as on the parasite's response against the host when the infection is established Chronic infections and inflammation along with unhealthy diet, stressful lifestyle, cell damage, constant exposure to radiation, and harmful chemicals are risk factors for the development of cancers As infectious factors, the Blastocystis hominis and Cryptosporidium spp. are opportunistic protozoa isolated from the human host gastrointestinal tract, These prevalent enteric parasites may cause serious challenges in people undergoing colorectal cancer treatment (chemotherapy)

Enrollment: 100 estimated patients

Sex: All

Ages: 2+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• intestinal cancer patients (colorectal cancer, intestinal lymphoma, gastrointestinal stromal tumors, and other malignant variants)

Exclusion criteria

• patient took antibiotics within the previous four weeks and anti-parasitic drugs within the previous two weeks

Trial design

100 participants in 2 patient groups

group A

Description:

• One hundred stool samples will be collected from patients with intestinal cancer admitted to Sohag Hospital.

Treatment:

Diagnostic Test: stool examination

group B

Description:

one hundred stool samples will be collected from the control group of patients who attended outpatient clinics

Treatment:

Diagnostic Test: stool examination