Evaluation of Intra Axial Brain Masses Based on Magnetic Resonance in Adults

Assiut University

Status: Unknown

Conditions: Brain Tumor

Treatments: Device: Magnetic resonance imaging with contrast

Study type: Observational

Funder types: Other

Identifiers

NCT03166592

IAM

Details and patient eligibility

About

Although the Magnetic resonance imaging with contrast is the gold standard for diagnosis of intra axial brain masses. The conventional Magnetic resonance imaging appearances of intra axial brain masses can be non-specific and even the use of contrast agent is of limited benefit.

Contrast enhancement reflects only disruption of blood brain barrier. One third of high-grade malignancies are non-enhanced and may non-neoplastic lesions show contrast enhancement.

Reliable differentiation of neoplastic from non-neoplastic brain masses, or of high grade from low grade tumor, is difficult with conventional Magnetic resonance imaging

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

1. Inclusion criteria:

   * An intra axial space occupying lesion/lesions detected on conventional structural imaging

2. Exclusion criteria:

   • MRI contraindications (as pace maker or claustrophobia).
   • Contrast hypersensitivity
   • Impaired renal function.
   • Pediatric age group