Evaluation of Liver Damage in Patients With Anorexia Nervosa by Blood Biomarker Analysis (BILAN)

Nantes University Hospital (NUH)

Status: Enrolling

Conditions: Anorexia Nervosa

Treatments: Other: Patients with Anorexia Nervosa

Study type: Observational

Funder types: Other

Identifiers

NCT06262165

RC23_0497

Details and patient eligibility

About

The main goal of the BIocoLlection in Anorexia Nervosa-liver damage evaluation BILAN study the blood biomarkers associated with liver cytolysis.

Full description

Study of the association between blood biomarkers and the presence of hepatic cytolysis, defined by AST and/or ALT above normal.

Enrollment: 50 estimated patients

Sex: All

Ages: 15 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria :

• Patient over 15 years old
• Diagnosis of Restricted Eating Disorders including Anorexia Nervosa according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)
• Admission to Nantes University Hospital.

Exclusion Criteria :

• Chronic active viral hepatitis
• Hemochromatosis
• Other genetic, autoimmune.
• Treatment with a drug known to induce fatty liver disease (amiodarone, carbamazepine, tamoxifen, valproate, clozapine, anti-retrovirals) unless the dose has been stable for ≥ 3 months
• Excessive alcohol consumption (≥ 30 grams per day in men, ≥ 20 grams per day in women)
• Pregnant, parturient or breast-feeding women, persons deprived of liberty, adults under legal protection or unable to express their consent, persons not affiliated or not beneficiaries of a social security scheme, persons under guardianship or curators